Studies that fail to establish significant benefits of an intervention like medication are often never submitted for publication and instead filed away. the problem with this approach is that

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The issue with this approach is that this inclination toward distributing just positive outcomes seriously constrains our capacity to assess the viability of antidepressants since we are just observing a cut of the real information. Further, a few scientists have addressed whether individuals with not as much as serious melancholy may have encountered positive outcomes in light of their desire of advantage, also called the misleading impact.